ido1 inhibitor 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T20513	IDO1-IN-1	IDO1 inhibitor 1,2 HzBTZ,IDO1IN1,2-HzBTZ,IDO1-inhibitor-1	IDO
	IDO1-IN-1 (2 HzBTZ) is an indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.		IDO
T11901	IDO1-IN-5		IDO , Indoleamine 2,3-Dioxygenase (IDO)
	IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T11625	IDO1 and HDAC1 Inhibitor		Others
	IDO1 and HDAC1 Inhibitor is a dual IDO1 and HDAC1 inhibitor (IC50s: 69.0 nM and 66.5 nM).		Others
T11616	IDO-IN-13	GS-4361	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	IDO-IN-13 (GS-4361) is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor (EC50: 17 nM).		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T4532	Linrodostat	BMS-986205	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T9164	BMS-986242	BMS986242	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T82082	IDO1-IN-23		Indoleamine 2,3-Dioxygenase (IDO)
	IDO1-IN-23 (compound 41) is a potent inhibitor of human indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an IC50 of 13 μM [1].		Indoleamine 2,3-Dioxygenase (IDO)
T61140	IDO1/TDO-IN-3
	IDO1/TDO-IN-3 is a powerful inhibitor targeting IDO1 and TDO enzymes. It displays noteworthy effectiveness against IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM). Additionally, IDO1/TDO-IN-3 demonstrates considerable in ...
T63651	IDO1/2-IN-1 hydrochloride
	IDO1/2-IN-1 hydrochloride is the first potent dual inhibitor of IDO1 (IC50: 28 nM) and IDO2 (IC50: 144 nM) that is orally active.IDO1/2-IN-1 hydrochloride exhibits antitumor effects.
T39888	IDO1-IN-7	IDO1-IN-7
	IDO1-IN-7, a potent and selective indoleamine-2,3-dioxygenase-1 (IDO1) inhibitor, exhibits high potency with an IC 50 of 6.1 nM in the cellular assay (SKOV3). Apart from its inhibitory properties, IDO1-IN-7 also demonstr...
T28175	Nitrobenzofuroxan	NSC 228079,NSC-228079,B-2789,B 2789,B2789
	Nitrobenzofuroxan, is a HIV-1 and IDO1 inhibitor.
T12668	(Rac)-IDO1-IN-5		Others
	(Rac)-IDO1-IN-5 is a racemate of IDO1-IN-5, a potent, selective, and brain-penetrating inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity. It specifically binds to apo-IDO1, which lacks heme, instead of mature he...		Others
T63780	IDO1-IN-16
	IDO1-IN-16 (I-1) is an IDO1 inhibitor that targets holo-IDO1 (IC50: 127 nM).
T61789	IDO1-IN-14
	IDO1-IN-14 (compound 4a) is a highly effective inhibitor of the IDO1 enzyme, exhibiting an IC50 value of 396.9 nM. Additionally, IDO1-IN-14 demonstrates excellent suppression of cellular IDO1 activity, as observed in HeL...
T63222	IDO1/2-IN-1
	IDO1/2-IN-1 is the first potent, orally active dual IDO1/IDO2 inhibitor, exhibiting antitumor effects with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively.
T60499	IDO1/TDO-IN-2
	IDO1/TDO-IN-2 (Compound 1) is a potent IDO1/TDO dual inhibitor with IC50s of 0.1 and 0.07 μM, respectively. IDO1/TDO-IN-2 has the potential for cancer research[1].
T60698	Roxyl-9
	Roxyl-9 is an inhibitor of IDO1 (Indoleamine 2,3-dioxygenase 1) [1].
T61385	IDO1/TDO-IN-1
	IDO1/TDO-IN-1 (30) is a highly effective inhibitor that targets both IDO1 and TDO enzymes with uncompetitive (Ki = 0.23 μM) and competitive (Ki = 0.73 μM) mechanisms, respectively. This compound, IDO1/TDO-IN-1 (30), exhi...
T78687	IDO1-IN-21		Indoleamine 2,3-Dioxygenase (IDO)
	IDO1-IN-21 (compound 10m), with an IC50 of 0.64 μM, acts as an IDO1 inhibitor and has demonstrated efficacy in suppressing tumor growth in murine models [1].		Indoleamine 2,3-Dioxygenase (IDO)
T78795	IDO1/TDO-IN-6		Indoleamine 2,3-Dioxygenase (IDO)
	IDO1/TDO-IN-6 (compound 11) is a dual inhibitor targeting IDO1 and TDO, exhibiting IC50 values of 2.25 μM for IDO1 and 2.89 μM for TDO. The compound further demonstrates Ki values of 1.9 μM for IDO1 and 3.1 μM for TDO, m...		Indoleamine 2,3-Dioxygenase (IDO)